Close association of HLA-B51 and B52 in Israeli patients with Behcet's syndrome.

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Close association of HLA-B51 and B52 in Israeli patients with Behçet's syndrome.

Epidemiological data, family history, clinical data, and HLA typing were studied in three groups of patients with Behçet's syndrome: six Israeli Ashkenazi Jews, 29 non-Ashkenazi Jews, and three Israeli Arabs. HLA-B51 and B52 were present in 24/38 (63%) and 8/38 (21%), respectively, of the patients compared with 13/151 (9%) of the control group for both cases, a relative risk of 18.2 and 2.8 res...

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Close association of HLA-B52 and HLA-B44 antigens in Israeli Arab adolescents with recurrent aphthous stomatitis.

OBJECTIVES To investigate the incidence and clinical features of recurrent aphthous stomatitis (RAS) among Israeli Arab adolescents and to determine the HLA typing profile in affected subjects. STUDY DESIGN Cross-sectional study. SETTING Junior high school in the largest Arab town in Israel. PARTICIPANTS Four hundred seventy-seven Israeli Arab junior high school students filled out a ques...

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Primary association of HLA-B51 with Behçet's disease in Ireland.

AIMS/BACKGROUND While a primary association of HLA-B51 with Behçet's disease (BD) in Japanese and Mediterranean patients supports an immunogenetic predisposition, this link is unclear in north western Europe. This study assessed HLA associations with BD, and HLA-B51 with certain clinical characteristics, in the Republic of Ireland, which has an ethnically homogeneous population. METHODS HLA-A...

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Association of MICA polymorphism with HLA-B51 and disease severity in Korean patients with Behcet's disease.

The HLA-B51 allele is known to be associated with Behcet's disease (BD) in many ethnic group. However, it has not yet been clarified whether the HLA-B51 gene itself is the pathogenic gene related to BD or whether it is some other gene in linkage disequlibrium with HLA-B51. Recently, the Triplet repeat (GCT/AGC) polymorphism in transmembrane region of the MHC class I chain-related A (MICA) gene ...

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 1991

ISSN: 0003-4967

DOI: 10.1136/ard.50.6.351